Portalak 667 mg-ml, syrup (500 ml)
 
PHARMACOLOGICAL EFFECT
Laxative drug. Lactulose under the influence of intestinal microflora breaks down in the colon into low molecular weight organic acids. The formation of acids leads to a decrease in the pH of the intestinal contents and the activation of its peristalsis. Along with this, the volume increases and the softening of the feces occurs. Under the influence of the drug, the formation of nitrogen-containing toxic substances in the proximal colon and their absorption into the systemic circulation also decreases. In addition, the movement of ammonium ions from the blood into the intestine is enhanced. ; The effect of the drug occurs within 24-48 hours after ingestion.
PHARMACOKINETICS
Lactulose is practically not absorbed from the gastrointestinal tract (no more than 3% of the accepted dose is absorbed), does not reduce the absorption of vitamins, does not cause addiction.
INDICATIONS
- constipation (including chronic); - the need to soften the stool for medical purposes (with hemorrhoids, the need for surgery on the colon and / or anus, pain syndrome after removal of hemorrhoids, the postoperative period); - intestinal dysbiosis; - hepatic encephalopathy; - hepatic precoma and coma (treatment and prevention); - hyperammonemia; - enteritis caused by Salmonella, Shigella, Salmonella carrier; - putrid dyspepsia syndrome (in young children as a result of acute food vleniye).